Correct!

Going to give another hint to 40.

40.  a) Part of the gameplay of this game involves obtaining 3 keys to open up 3 different gates.  Kinda like the plot to Ready Player One.
b) This is the first game to ever give credit to the game's maker(s).  Although in this case the credits were hidden.

Aww Jeez. I thought Megaman 3 was the last of the great NES megaman games. Guess I'll have to pickup Megaman 4 then. Added to my wishlist.

Also, I love PS2 era Level-5. Rogue Galaxy will get played eventually. My backlog is too big. :P

Yeah, original CoD4 was so revolutionary for it's time. These days, that sort of gameplay is a dime a dozen, but throwing RPG elements into a multiplayer game was such a step up at the time.

@mZuzek What program are you using to make these cards? Anything that's more affordable than photoshop's $10 monthly fee?

I had no idea this existed. Adding it to my GBA Wishlist. Treasure games are a um... Treasure? Yes. :P

Another game sitting in my backlog. The really good news for Switch owners is that since PS5 isn't doing too hot in Japan, and since PS4 didn't do all that well, a lot of Japanese RPG devs are going to prioritize Switch, and then release on PC a few months later. PS5 might not actually get a lot of these niche JRPGs anymore, since the PS4 sold poorly in Japan, and PS5 is looking to do even worse.

I had the same problem with Persona 5. The story at times just holds your hand, and not much happens for an hour or so. But then once the major plot points kick in it gets really good.

#49 - Guardian Heroes - Xbox 360

An incredible beat em up from Treasure, besides its great, stylish sprite work, its memorable soundtrack, GH offers a cool, replayable adventure thanks to its branching paths and stories on top of its multiple characters and light level up system, story is wacky as a trademark of the studio, gameplay is satisfying and challenging enough, just a ton of fun.

#48 - Ys Origin - PC/NS

Best Ys game, as a prequel it manages to get a lot right in setting up the events of I & II, with a good enough story that doesn't drag too much in its exposition, at this point I have only done Yunica's route from the 3 playable characters, really like her, is like an Adol but with more personal drive and a personality. One of my favorite things about playing Ys games are the bosses, and Origin delivers well on creating very fun ones, they are the driving force of challenge in the series, between the zen grinding sessions in the levels, another of my favorite things from it is the music, I love the tower structure, every time I finish a boss I know I'll get to hear a new music track for the next main floor, this soundtrack in particular being my favorite of the series, and another thing I appreciate the most from the series up to this point, the simplicity and short lenght, is a nice, comfort ARPG.

Yeah, I've heard some people say that, but I always thought 4 was very much on par with 2 and 3, though I'm sure people's opinions differ greatly on that topic. Also, I actually just started replaying Rogue Galaxy a few days ago, and so far I'm really enjoying it. The PS4 digital release is a nice way to go back to it.

#48: One of the latest games for the Neo-Geo, but also one of the best - and certainly the best of it's series

Hint: In this remake of an early title of this series, you first fight through an army of soldiers, but end up fighting off an alien invasion halfway through the game.

#46: Summon Volcanoes or dig craters in this very innovative shooter/genre mix

Hint #1: Has an Arabian Nights setting.

Hint #2: You need to built a castle to collect the Mana of the world Magic Carpet 2, found out by Mnementh

#41: Greetings, Warlord! Let the war begin! 

Adventure

Also, the idea for the 3 keys and 3 gates (shortened to just the 3 keys in the movie) is certainly coming from this game. It even shows up in the last challenge in the movie.

I don't know anything about the game, but I heard about the credits. That was Atari don't credit their devs, so Robinett made an secret room with the credits in Adventure.

EDIT: I see @Bofferbrauer2 was faster.

Wait, is #46 Magic Carpet?

After Doom revolutionized the 3D games many games tried to push the envelope. Descent took a direction only few others took: a fully 3D-experience by setting it into space and allowing to move and turn in each direction. This was called six degrees of freedom.

This makes controlling a bit difficult, not because the controls are complicated, but because you have to get in a mindset of full movement freedom and the ability to keep track of your position. So the challenges aren't the enemy robots alone, finding the right path without getting lost is a challenge in itself. And extremely satisfying if you're able to pull it off.

This is demonstrated each level, as you have to find the exit after destroying the reactor which explodes after that. You have to reach the exit in time before the mine explodes and destroys you too. As navigating is a challenge, this meant I died quite a few times trying to find my way to the exit.

As you can go not only left and right, but also up and down, the level design can quite intricate. To support you, the game gives you a freely movable automap realized with wireframe models.

Other than the level-design and navigation challenge the game features more or less all that Doom had set as a precedent: destroy the enemies (in this case mining robot drones that were infected with a virus that made them rebel), finding keycards to open color-coded doors, collecting weapons, ammunition and items that float around. As an additional feature you can rescue the human staff, that is taken hostage by the robots, for extra points.

The story is simple. In the future (the year 2169) companies have started mining on different celestial objects in the solar system. For this many mining robots are used. A virus overtakes these robots, so that they rebel against their human owners. You are sent to end this danger.

To play it today, you can use Dosbox as usual to emulate DOS. That works well. If you don't own the game, you can as so often rely on GOG, where it already packaged into a Dosbox-emulation. Also you can play for free in the browser on archive.org, emulated in Javascript. As usual with this browser emulation, your performance may have issues, depending on your system and your browser. As I just saw, there is also a project called DXX-Rebirth, which provides a modern engine for the Descent game files. I haven't tried it yet, but seemingly it improves resolution and uses modern graphic card features.

As DXX Rebirth offers clearer visuals, I use a video from that project. The original game is the same, but with lower resolution.

https://www.youtube.com/watch?v=SJ8IqaxBR6I

Time for the next game to guess. And #37 is unguessed so far, so I add a hint.

#40: Resident Evil as guessed by UnderwaterFunktown

#39: Baldur's Gate III guessed by UnderwaterFunktown
After 20 years finally we get the third mainline entry, for the moment in early access.

#38: Pikmin guessed by cosmic_drift
Your spaceship crashed on this strange planet and you need to find it's missing parts.

#37
Your first task: dig out a skull.
Said skull gives you pointers what to do next.

#36: Assassins Creed Odyssey guessed by Jpcc86
Climb enormous statues of gods to enjoy the view.