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Forums - General Discussion - Coronavirus (COVID-19) Discussion Thread

Patrick Batman sitting at a table with a Joker.

Funny thing, he actually WANTS Corona.



I describe myself as a little dose of toxic masculinity.

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numberwang said:

The leading 'Oxford' mRNA vaccine has been paused.


Severe illness (transverse myelitis) developed.
A leading coronavirus vaccine trial is on hold: scientists react


It failed in animal trials anyway.

"There was no difference in the amount of viral RNA detected from this site in the vaccinated monkeys as compared to the unvaccinated animals. Which is to say, all vaccinated animals were infected"
Doubts over Oxford vaccine as it fails to stop coronavirus in animal trials

2/3 have side effects like pain, fever, fatigue etc. Had to used with painkiller paracetamol to ease the side effects. 
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31604-4/fulltext#

Did the UK have more than 1 vaccine in developement?
They refused to be part of the european developement of a common one right? I think EU has a few in developement currently.

Also any news on how the russian one went? They were at a state were they were gonna skip the last phase of testing right?
Does that one appear to work?



numberwang said:

It failed in animal trials anyway.

"There was no difference in the amount of viral RNA detected from this site in the vaccinated monkeys as compared to the unvaccinated animals. Which is to say, all vaccinated animals were infected"
Doubts over Oxford vaccine as it fails to stop coronavirus in animal trials

Curious how the media chose to present it when the title of the scientific article was something entirely different.

https://www.biorxiv.org/content/10.1101/2020.05.13.093195v1

Sterilizing immunity is not protective immunity. This is anything but a failure: true failure in vaccination yields spectacularly bad results such as making a mild disease outright kill you, making you vulnerable to something else, outright infecting you with a poorly inactivated vector, etc.



 

 

 

 

 

The US has officially surpassed 200,000 deaths attributed to Coronavirus which now breaks the worst-case scenario of the middle of the road predictions by the White House experts. Although the excess death rate for 2020 is significantly higher than 200K; the blame for this can go to right-wing governments suppressing numbers who encourage careless behaviour and now need to prove it didn't create mass deaths across the US. Can the US still be considered a western country with such a decline of common sense running the country? Europe has its problematic idiots who are preventing us from eliminating the virus, but they haven't been allowed to dominate the culture and rules as Americans have allowed them to do so in the US.


https://www.npr.org/sections/coronavirus-live-updates/2020/03/29/823517467/fauci-estimates-that-100-000-to-200-000-americans-could-die-from-the-coronavirus#:~:text=The%20nation's%20leading%20expert%20on,Dr.

I hope Americans finally learn their lesson with this one and stop acting like "We're gonna fix all your problems! Only we can fix the world!" "But... you guys are doing worse than all of us... significantly so." "Nah! We just need to elect people with no experience in government to save you!"
I really hope this American mentality stops, and that they start trying to work with the rest of the world on global issues, not be the stupid kid in the class trying to lead the class project.

Last edited by Jumpin - on 16 September 2020

I describe myself as a little dose of toxic masculinity.

numberwang said:

The leading 'Oxford' mRNA vaccine has been paused.


Severe illness (transverse myelitis) developed.
A leading coronavirus vaccine trial is on hold: scientists react


It failed in animal trials anyway.

"There was no difference in the amount of viral RNA detected from this site in the vaccinated monkeys as compared to the unvaccinated animals. Which is to say, all vaccinated animals were infected"
Doubts over Oxford vaccine as it fails to stop coronavirus in animal trials

2/3 have side effects like pain, fever, fatigue etc. Had to used with painkiller paracetamol to ease the side effects. 
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31604-4/fulltext#

Just a routine check; it's been resumed: https://www.abc.net.au/news/2020-09-13/astrazeneca-oxford-university-resume-coronavirus-vaccine-trial/12658984 

Your third link even states "all participants had neutralizing activity" and Phase I and II human trial results have shown that it produces a "strong immune response" and "no serious adverse health effects": https://www.ox.ac.uk/news/2020-07-20-new-study-reveals-oxford-coronavirus-vaccine-produces-strong-immune-response

Last edited by curl-6 - on 16 September 2020

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Jumpin said:

The US has officially surpassed 200,000 deaths attributed to Coronavirus which now breaks the worst-case scenario of the middle of the road predictions by the White House experts. Although the excess death rate for 2020 is significantly higher than 200K; the blame for this can go to right-wing governments suppressing numbers who encourage careless behaviour and now need to prove it didn't create mass deaths across the US. Can the US still be considered a western country with such a decline of common sense running the country? Europe has its problematic idiots who are preventing us from eliminating the virus, but they haven't been allowed to dominate the culture and rules as Americans have allowed them to do so in the US.


https://www.npr.org/sections/coronavirus-live-updates/2020/03/29/823517467/fauci-estimates-that-100-000-to-200-000-americans-could-die-from-the-coronavirus#:~:text=The%20nation's%20leading%20expert%20on,Dr.

I hope Americans finally learn their lesson with this one and stop acting like "We're gonna fix all your problems! Only we can fix the world!" "But... you guys are doing worse than all of us... significantly so." "Nah! We just need to elect people with no experience in government to save you!"
I really hope this American mentality stops, and that they start trying to work with the rest of the world on global issues, not be the stupid kid in the class trying to lead the class project.

This about sums it up. America needs to realize that electing the dumbass reality TV star wasn't good for them. The only way it's 'good' is if you're super racist and hate poor people/women/non-whites/foreigners/non-christians....

but that's a rant for a different thread. 

They're also stupid when it comes to science. Did you hear they actually elected a climate-change denier to the highest office in the field of ecology or something? yeah. dumbasses. 



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curl-6 said:
numberwang said:

The leading 'Oxford' mRNA vaccine has been paused.


Severe illness (transverse myelitis) developed.
A leading coronavirus vaccine trial is on hold: scientists react


It failed in animal trials anyway.

"There was no difference in the amount of viral RNA detected from this site in the vaccinated monkeys as compared to the unvaccinated animals. Which is to say, all vaccinated animals were infected"
Doubts over Oxford vaccine as it fails to stop coronavirus in animal trials

2/3 have side effects like pain, fever, fatigue etc. Had to used with painkiller paracetamol to ease the side effects. 
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31604-4/fulltext#

Just a routine check; it's been resumed: https://www.abc.net.au/news/2020-09-13/astrazeneca-oxford-university-resume-coronavirus-vaccine-trial/12658984 

Your third link even states "all participants had neutralizing activity" and Phase I and II human trial results have shown that it produces a "strong immune response" and "no serious adverse health effects": https://www.ox.ac.uk/news/2020-07-20-new-study-reveals-oxford-coronavirus-vaccine-produces-strong-immune-response

You are repeating their own marketing spin, not a reliable source. I am referencing the actual clinical outcome data and it is terrible. A vaccine that doesn't reduce infections and viral load has no way to increase herd immunity. Taking Vitamin D would likely give better immunity.

The clinical outcome of this vaccine:

71% fatigue

68% headaches

60% systemic muscle ache

61 malaise

51% feverish

18% fever over 38°C

Injecting painkillers to hide these symptoms for a vaccine is unacceptable. We are not talking about a rare medication for a last ditch effort to save someone but a vaccine that is supposed to be given to healthy people.

Fatigue was reported in the ChAdOx1 nCoV-19 group by 340 (70%) participants without paracetamol and 40 (71%) with paracetamol and in the MenACWY group by 227 (48%) participants without paracetamol and 26 (46%) with paracetamol, whereas headaches were reported in the ChAdOx1 nCoV-19 group by 331 (68%) participants without paracetamol and 34 (61%) with paracetamol and in the MenACWY group by 195 (41%) participants without paracetamol and 21 (37%) participants with paracetamol.
Other systemic adverse reactions were common in the ChAdOx1 nCoV-19 group: muscle ache (294 [60%] participants without paracetamol and 27 [48%] with paracetamol), malaise (296 [61%] and 27 [48%]), chills (272 [56%] and 15 [27%]); and feeling feverish (250 [51%] and 20 [36%]). In the of ChAdOx1 nCoV-19 group, 87 (18%) participants without paracetamol and nine (16%) participants with paracetamol reported a temperature of at least 38°C, and eight (2%) patients without paracetamol had a temperature of at least 39°C. In comparison, two (<1%) of those receiving MenACWY reported a fever of at least 38°C, none of whom were receiving prophylactic paracetamol


numberwang said:
curl-6 said:

Just a routine check; it's been resumed: https://www.abc.net.au/news/2020-09-13/astrazeneca-oxford-university-resume-coronavirus-vaccine-trial/12658984 

Your third link even states "all participants had neutralizing activity" and Phase I and II human trial results have shown that it produces a "strong immune response" and "no serious adverse health effects": https://www.ox.ac.uk/news/2020-07-20-new-study-reveals-oxford-coronavirus-vaccine-produces-strong-immune-response

You are repeating their own marketing spin, not a reliable source. I am referencing the actual clinical outcome data and it is terrible. A vaccine that doesn't reduce infections and viral load has no way to increase herd immunity. Taking Vitamin D would likely give better immunity.

The clinical outcome of this vaccine:

71% fatigue

68% headaches

60% systemic muscle ache

61 malaise

51% feverish

18% fever over 38°C

Injecting painkillers to hide these symptoms for a vaccine is unacceptable. We are not talking about a rare medication for a last ditch effort to save someone but a vaccine that is supposed to be given to healthy people.

Fatigue was reported in the ChAdOx1 nCoV-19 group by 340 (70%) participants without paracetamol and 40 (71%) with paracetamol and in the MenACWY group by 227 (48%) participants without paracetamol and 26 (46%) with paracetamol, whereas headaches were reported in the ChAdOx1 nCoV-19 group by 331 (68%) participants without paracetamol and 34 (61%) with paracetamol and in the MenACWY group by 195 (41%) participants without paracetamol and 21 (37%) participants with paracetamol.
Other systemic adverse reactions were common in the ChAdOx1 nCoV-19 group: muscle ache (294 [60%] participants without paracetamol and 27 [48%] with paracetamol), malaise (296 [61%] and 27 [48%]), chills (272 [56%] and 15 [27%]); and feeling feverish (250 [51%] and 20 [36%]). In the of ChAdOx1 nCoV-19 group, 87 (18%) participants without paracetamol and nine (16%) participants with paracetamol reported a temperature of at least 38°C, and eight (2%) patients without paracetamol had a temperature of at least 39°C. In comparison, two (<1%) of those receiving MenACWY reported a fever of at least 38°C, none of whom were receiving prophylactic paracetamol

You're cherrypicking, and none of those side effects are serious, it's all minor, effectively harmless stuff.

From the same clinical data:

"No serious adverse reactions to ChAdOx1 nCoV-19 occurred". 

"In conclusion, ChAdOx1 nCoV-19 was safe, tolerated, and immunogenic, while reactogenicity was reduced with paracetamol. A single dose elicited both humoral and cellular responses against SARS-CoV-2, with a booster immunisation augmenting neutralising antibody titres. The preliminary results of this first-in-human clinical trial supported clinical development progression into ongoing phase 2 and 3 trials".

Last edited by curl-6 - on 16 September 2020

haxxiy said:
Barozi said:

"Positivity rates around 1% are irrelevant and interchangeable considering noise from false positives or sample contamination."

That's not the point. The point is that it took ages for Sweden to get close to 1% while many many other countries have been around 1% for months.

"Besides, both Norway and Denmark now have higher cases per capita, and even in absolute cases, if we are talking about Denmark."

I'm not blindly going to believe the first part but I'm not in the mood to find their data. Let's just say even if it's true, it's probably not far off from Sweden's current numbers, so by your definition just statistical noise.

The second part of that statement however is just misleading at best and plain wrong at worst. Denmark currently has more confirmed cases because they are testing far far more people. ~45k daily tests (0.78% of the population) vs. 18k daily tests (0.18% of the population) (based on 126k tests last week).

That's roughly 4 times more tests per capita in Denmark compare to Sweden. You talk about confirmed cases while it's obvious that Sweden's true daily case count is quite a bit higher than Denmark's.

If they are testing less per capita, wouldn't their positivity rate by default be higher, then? Or do you believe they're just blindly stumbling into positives?

I understand you wouldn't be in the mood to research data that contradicts your point of view (it's all freely available in Our World In Data, by the way) but don't expect me, then, to accept your logical inference, without any study to back it up, that Sweden MUST have more cases just because you think so.

Here's something to think about:

https://www.aa.com.tr/en/europe/germany-covid-19-cases-rise-as-schools-reopen/1941262

Vs.

https://www.tellerreport.com/news/2020-09-07-here-the-mass-tests-continue-on-campus.By7ssdTX4v.html

It's not my fault you can't follow my logic. I mean you could if you knew basic maths but that seems to be a severe problem for you.

Sweden currently has more daily cases (in absolute terms) than Denmark.

That's what I already proved. I already gave you all the numbers you need to come to the same conclusion but it's understandable that you won't acknowledge data that contradicts your point of view.

You think I don't know that the amount of testing has no effect on the positivity rate? Please, that's more than obvious. No need to point it out.
But you seem to think that every single person that gets tested outside the group of people who would've been tested either way, is an automatic negative. That's not true at all and the huge problem in your logic. It's also incredibly obvious that the days of primarily testing people with symptoms are long over. So yeah, they are indeed blindly stumbling into a lot of positives because A) the testing capacity is there and B) the authorities want to test as many people as possible to keep everything under control.

I bet if you read an official source saying that one case of rape is reported to Indian authorities each year, you would blindly believe it even when someone points out that this is only the official count and it's happening in the hundred thousands to maybe millions without getting reported.
I can already hear you say: "don't expect me to accept, without any study to back it up, that India must have more rape cases just because you think so."

You can tell even without studies. It's called logic.



Interesting observation, glasses might help prevent infection

https://www.ctvnews.ca/health/coronavirus/new-study-makes-curious-observation-hospitalized-covid-19-patients-were-less-likely-to-wear-glasses-1.5109849

The researchers hypothesized that wearing glasses might have prevented some spread of the virus due to the glasses discouraging “wearers from touching their eyes, thus avoiding transferring the virus from the hands to the eyes.”

They noted that previous research has shown that the enzyme that SARS-CoV-2 (the virus that causes COVID-19) uses as a receptor is in abundance on the surface of the eye.

Kinda makes sense stated that way. My glasses also help to keep the face mask snug around my nose.