See here for the current standing in the guessing game.

#20: Baldur's Gate as guessed by Darashiva.

#19:
The game has some innovative ideas, mainly it tries it's hand at procedural story generation and character growth, meaning each playthrough is different.
First the Age of Ulstryx.
Meet Drauven, Thrixl, Morthagi.
This kinda obscure indie game came to PC in 2021.

#18: Breath of the Wild as guessed by Darashiva.

#17: (not Outer Wilds)
20 minute survivors.
Shoot at these spawning horrors to survive until dawn.
A good art style only needs black, white and red.

#16: Kid Icarus: Uprising as guessed by S.Peelman.
"Sorry to keep you waiting!" ... does a simple sorry cut it, if the wait was 26 or 21 years (depending on the region)?
"I can't believe I'm actually flying!" - yes, in this game he does.
"Here to crash my homecoming party?" - that says the final boss of the first game and the final (???) boss of this one.

#15:
Let's rise your settlement, before it falls again to Ruins.
Build your city and defend against the hordes of the corruption attacking at night.

#14:
On the first day man was granted a soul and with it, clarity.

Hold on to that guess! It's coming up. But it's not #20.

Well, my other thought was Super Mario Galaxy, because of Super and Galaxy is all-encompassing.

Oh wait.

Kid Icarus Uprising?

Yes, finally. Took long enough.

You were closer with Metroid Prime. This game surely deserves a perfect score.

Someone has surely got to get 22. One of the clues has also been used by someone else recently as well so no excuses now!

22 - Banjo-Kazooie
- As you play through this game, it helps to pay attention to what you’ve seen, what you’ve heard, and what you’ve been told, as that knowledge will come in handy later.
- One of the titular characters in this game first appeared in an earlier game (of a different genre) from the same developer.
- The titular character mentioned above can take flight in both games, although his method for doing so is different in each game.
- The method for the titular character mentioned above taking flight in this particular game involves using a physical feature of the other titular character.
- Kudos to the bird for having the strength to carry that bear.

19 - The Legend of Zelda: Tears of the Kingdom
- A glitch to quickly and substantially increase your item numbers was just one of many things people discussed about this game this year.
- Introduced bubbly, cave dwelling creatures to the franchise.

18
- Be kind to nature and nature will be kind to you.

Current list - https://gamrconnect.vgchartz.com/thread/247804/the-official-thread-the-14th-annual-greatest-games-event-post-only-once/4/#3

Ah I got it, Perfect Dark

22- Bajo Kazooie obvs. Soutout to Rare for being awesome like 2 and a half decades ago. 

19.- Tears of the Kingdom? I know cause I got rich with that glitch. That rhymed and it wasnt even on purpose. 

18.- Im gonna say Animal Crossing even tho I do know its not Animal Crossing. 

You and me both got rich off that glitch in Tears of the Kingdom. Cut down on the tedium and then some. And yes, Banjo Kazooie is correct for number 22.

18 is incorrect, but I almost want to give you points just for making me laugh with your answer.

So there you go, as the great Meat Loaf (RIP) once sang (and the great Jim Steinman, also RIP, wrote), two out of three ain't bad.