Aw fuck yeah!  #47 is Mass Effect.

Took ya long enough.

By the way, the song is M4 (Part II) by Faunts. It playing at the end credits was always super memorable to me, seems I'm in a minority then. Either way, great song.

In my defense, I just woke up. lol

That's a long time to be sleeping, I hope all's well over there.

Either way, the next day is upon us, so here's another hint. In the meantime I'll be sorting my individual posts and am aiming to flood the thread with many of them sooner rather than later.

I guess there's some need for a couple hints here:

50: Probably the best PC-exclusive beat'em up One Must Fall 2097, as found out by Mnementh

1. Hint: You play giant robots called HARs that duke it out.

48: No transformations in this entry of the series despite it being a series staple

1. Hint: Instead, you use the equipment of a former enemy in this game.

47: This early 3D PC game is mostly an ego-shooter, but also an adventure game and has some strategy mixed into it.

1. Hint: As long as you have summoned a castle and it is still standing, getting killed will respawn you there, otherwise it's game over.

46: This Wii game is almost all in Black and white, save for some red and yellow sprinkled in. MadWorld, as found out by coolbeans

Scoreboard:

Top 50 games list:

#46 sounds like MadWorld.

That's the right sound!

It was a pretty easy one, though

#47
- Destroying speakers will stop music playing in that particular part of the level.
- Due to a bug, it's impossible to collect everything in the original version of the game. To access the secret level, you have to use a cheat code or an Action Replay.
- The developer was rebranded and went on to produce some of the biggest selling games in history.
- You often have to control various animals in each level to complete certain tasks, and then make your way to the teleporter to exit.

#46
- Challenging, highly regarded old school Zelda-like that was exclusive to one of Nintendo’s rivals.

#50: OK, I want on this scoreboard. I wanted to answer with your first hint already, but I thought: "nah, there are so, so many fighting games on the PC, basically everything you can think of, it can be the best for him and me". But well, Human Assisted Robots, it is One Must Fall: 2097. After being on my #50 spot in 2017 it moves around just below 50. I want to add this game is not simply from Epic, it is from Epic MegaGames (how does that sound!). I love the news commentator reporting about the fight and your mechanic giving you shit if your robot took too much damage. And back then it had secret crossover fighters like Jazz Jackrabbit.

Hmm, Okami was exclusive to PS2 for a time, before it got everywhere.