Let's add more hints:
#45: Ys VIII: Lacrimosa of Dana as guessed by Veknoid_Outcast.
#44: Pikmin 4 as kind of guessed (right series) by S.Peelman.
#43: Deathloop as guessed by Machina.
#42: Grounded as guessed by Darashiva.
#41: Starcraft/Broodwar as guessed by UnderwaterFunktown.
#40: Songs of Conquest as guessed by The_Liquid_Laser.
#39: (not Earth Defense Force)
The monsters come out on friday, but the Earth Defense Force will protect us!
Or Laundry Cleaner Man might also help.
That's just Frank.
#38:
Another recent-ish game that is the spiritual successor of an much older game, this time made by the original creator of the first game.
Fight the mutants caused by the extraterrestrial virus that was freed by climate change and the melting permafrost.
#37:
How many cruise ships are there?