I know this isn't a Wii game, but I can't help it. Playing the game made me miss the RE4 Wii controls. RE5 just seems slow to and cumbersome to move and aim. I haven't played enough to say whether the game will be good, but it's difficult to enjoy it when all I can think about is how unnatural the controls are. The graphics are nice, but to be honest they don't really increase my enjoyment of the game very much.

That did spark my interest.  I had ignored that game due to mediocre reviews.  In reading the IGN review, however, I came across this:

" Players should be warned, however, that - as with other Wii games of its nature - Ghost Squad doesn't work exactly like a light gun. Most Wii gun games thus far have used the IR as a mouse, having players hold the controller in a comfortable position and doing little more than steering a target around the screen, and that's the default feel with Ghost Squad as well. You aren't aiming at the screen, but the sensor bar. With the release of the Zapper, however, Nintendo is hoping to make these games feel more in tune with actual light-gun titles, though Ghost Squad did so with a simple calibration screen rather than rocking a plastic shell that is essentially a light gun placebo. Ghost Squad allows you to turn off the on-screen cursor, adding to the difficulty while offering a higher overall score burst. Rather than having players rely on guess work, however, the Wii-mote can be sighted in via an IR calibration screen, at least to a certain extent. Shoot the upper-left and bottom-right of the screen with the controller and you're in business, although it'll still have some issues throughout.

 As Since the IR works on triangulation, the center of the screen will be more accurate than the outsides, so while looking down the "barrel" of the Wii-mote will actually work, the cursor will get progressively farther from your aim as you near the edge of the screen in any direction. Also, you'll need to hold the Wii-mote (or Zapper controller) extremely level, as any tilt at all in the IR will result in skewed aim. As a final oddity, any forward or backward movement after calibration will also throw the triangulation off, so once you sight it in, you'll need to stay in that same position until you're done playing. It's a solid first effort in trying to truly calibrate the IR, but as fair warning to those looking to play Ghost Squad in the more traditional light gun mode, it still isn't perfect. Our suggestion for scoring massive points: Use the unlockable TM9V pistol with the "laser sight" as its special ability. You can turn off the cursor, and still have a tiny dot on-screen at the sacrifice of automatic weaponry or overwhelming power."

It doesn't appear that it's very accurate.  I don't think the IR tech in the Wiimote is going to produce enough accuracy to dethrone a 1600dpi mouse any time soon.  I think they need more sensors around the TV. or at least better calibration.  Not being able to move the controller much isn't going to work.

Indeed, but RE 1 redeemed itself with the awesome cutscenes and dialogue!

"You, Jill, the master of unlocking." -lengthy pause while the PS makes weird noises-

That's not what would fix the game though. Yes, RE4 Wii's controls were more accurate, but this isn't just about accuracy. The character himself controls awkwardly and sluggishly. The aiming is much slower than necessary with an analog stick. This isn't about Wii controls. This is simply an unacceptably poor use of analog controls.