Some of my thoughts on some of the entries:
#1 The Legend of Zelda: Breath of the Wild - I am fine with that, it is a brilliant game, despite its flaws, and it easily made my top 50 as well. I don't think it will remain at the top of these lists in the future though. If the sequel manages to address some of BotW's mistakes, I think it can become an even better game, then the votes between BotW and BotW2 will be split.
#2 Super Mario Galaxy - Also a great choice, it didn't quite make my list, but it easily could have. I think the sequel might be slightly better, and I am surprised how much lower that is on the list.
#4 The Legend of Zelda: The Wind Waker - This game really belongs in the academy of overratedness. It was mocked upon release because of the presentation. Years later this has been severely reevaluated by the mainstream, and rightfully so, the presentation of the game is fantastic, unfortunately everything else is aggressively average. The dungeon design is weak, the exploration is not particular rewarding, the game is surprisingly linear, and the pacing is dragged down by repetetive sailing and boring fetch quests. It is a solid game, but not much more.
#6 Super Mario Bros. 3 - Great to see this so high! And rightfully above Super Mario World!
#9 - Super Metroid - Still embarrassed I haven't played this.
#24 Hollow Knight - Great to see so much love for this!
#25 The Witcher 3 - Had it not been for the strong Nintendo bias here, I think this would have easily cracked the top 10, but #25 is certainly respectable and well earned!
#29 Resident Evil 4 - This should probably be even higher.
#34 Pokemon Gold/Silver/Crystal - Just played this again for the first time in many years. While the franchise is really overrepresented considering how little it has evolved, I think Gold/Silver/Crystal are truly masterful games. It really perfected the formula and kept the simplistic 8-bit charm that is very important to the experience I think. The remakes are kind of pointless in my opinion, and don't deserve to share the spot.
#50 Minecraft - I will never understand people's fascination with this game, but well, I can't deny the impact and influence.
#80 Mega Man 2 - So happy to see this classic make the top 100!
#82 Sonic the Hedgehog 2 - Same as Mega Man 2, so happy to have it in the top 100. Then Sega and the Genesis also got some representation.
#85 DOOM (2016) - Disappointing that this is above the much more polished and perfect DOOM (1993), but it is a solid game in its own right, even with its obvious modern game design flaws. It has already aged more than the original I feel. But at least it is this game that made the top 100 and not the god-awful DOOM Eternal.
#102 Starcraft - Kind of happy to see this NOT make the top 100, I never understood the hype.
#106 The Legend of Zelda: Link's Awakening - Unfortunate it didn't make top 100. I replayed it after I submitted my list. It would have made the cut, had I made my list afterwards. I think it is a stronger game than A Link to the Past.
#110 Half-Life 2 - Sucks to see this fall off top 100. It is fantastic and important.
#115 Resident Evil 7 - I put it high on my list, hoping it would make it into top 100, it came so close. I really admire this game!
#133 Civilization IV - Would have loved to have this in the top 100 as last year, hope it will be back next year.
#201 Tetris - This needs to be much higher one the list. The genre is kind of underappreciated.
#247 Metal Gear Solid V: The Phantom Pain - I think this deserves more love.
#310 Alien: Isolation - What the heck, only one person besides me voted for this? Have people not played this masterpiece?