The one-shot strategy was a resounding success I might add. GG UK.

To show how hard it is to escape the discerning gaze of cellular immunity, these are the results for T-Cell response to all VoCs out there. The two numbers represent respectively number and magnitude of preserved epitopes vs. the basal virus:

CD4+ T-Cell

84.4% - 89.6% B.1.1.7 (UK)
88.1% - 90% B.1.351 (SA)
95.7% - 94.3% P.1 (Brazil)
97.8% - 97.1% CAL20C (US)

CD8+ T-Cell

100% - 98.3% B.1.1.7 (UK)
97.3% - 98.4% B.1.351 (SA)
97.3% - 97.9% P.1 (Brazil)
97.9% - 97.8% CAL20C (US)

https://www.biorxiv.org/content/10.1101/2021.02.27.433180v1

Been put on a list to get my vaccine early. Could get it as soon as next month.

Weekly update, no much progress


In total 2.68 million new cases were reported last week (down from 2.74 million) bringing the grand total to 116,660,186 detected cases
Another 62.8K more deaths were reported as well (down from 65.9K) to a total of 2,591,302 casualties

Parts of Europe are on the rise again, USA still declining. At least deaths are still declining.

The continents

Europe reported 954K new cases (slightly down from 982K) and 21,925 more deaths (slightly down from 22.295)
South America reported 583K new cases (slightly up from 555K) and 14,239 more deaths (up from 12,506)
North America reported 550K new cases (down from 633K) and 18,502 more deaths (down from 21,857)
Asia reported 529K new cases (up from 499K) and 6,010 more deaths (down from 6,738)
Africa reported 67.7K new cases (down from 73.1K) and 2,103 more deaths (down from 2,455)
Oceania reported 423 new cases (381 last week) and 5 deaths (4 last week)

Corners of the world

USA reported 457K new cases (down from 533K) and 12,481 more deaths (down from 15,336)
Brazil reported 414K new cases (up from 376K) and 9,960 more deaths (up from 8,033)
India reported 113K new cases (up from 102K) and 723 deaths (730 last week)
Iran reported 58.3K new cases (slightly up from 57.0K) and 613 deaths (558 last week)
Canada reported 16.9K new cases (down from 20.9K) and 236 deaths (339 last week)
South Africa reported 8,201 new cases (down from 10.1K) and 782 deaths (925 last week)
Japan reported 7,256 new cases (7,505 last week) and 397 deaths (448 last week)
South Korea reported 2,732 new cases (2,778 last week) and 42 deaths (35 last week)
Australia reported 63 new cases (40 last week) no deaths

Europe in detail

Italy, Poland, Germany, Ukraine, Sweden and Norway are rising, the rest either flat or slowly declining. The wave that never seems to end.

Reported cases in Israel are still not really declining, flattened out slowly rising, despite half the population now having received a shot. (53.2 percent one dose, 39% second dose) I guess since all the vulnerable people receive shots first, those who keep themselves save anyway, real decline won't show up until the young and restless get their shots. Reported deaths are on a steady decline in Israel.

They would if people interacted randomly like cattle. No wonder, then, the concept of herd immunity comes from veterinary medicine.

Since you'll have younger people mostly interacting among themselves, and the same, I suppose, for more vaccine-skeptic groups like orthodox Jews, the rest of the population being vaccinated will mean nothing in terms of the reproduction rate of the virus among these populations.

Yup, spells good news for all countries. 

Severe Covid-19 cases over the age of 85 - 90 have dropped 50 - 70% since the beginning of vaccination in late January, according to multiple preliminary reports, here in Brazil. This would suggest a single dose of the Oxford/AZ or the Sinovac vaccines are proving to be effective in the most immunologically vulnerable age group, even in the face of the P1 variant, which is dominant in most states now.

These are absolute numbers of the entire age group (vaccinated or not), by the way; considering the prevalence of the disease has increased up to 40% among other age groups, the proportional reduction is more like 70 - 80%.

https://zeynep.substack.com/p/long-covid-how-bungle-reporting-on

An interesting and very thorough article on "long Covid" and the problems both with studies and reporting by media outlets.

Weekly Update, Europe is not giving up, creating more cases :/

The world reported 2.94 million new cases last week (up from 2.68 million) bringing the total to 119,597,209 detected cases
Another 59,597 people lost their lives (down from 62,784) bringing the total casualties to 2,650,899

The USA is on the right track, Europe is increasing again. Both are still reducing the number of deaths.

The continents

Europe reported 1.10 million new cases (up from 954K) and 20,895 more deaths (down from 21,925)
South America reported 680K new cases (up from 583K) and 16,074 more deaths (up from 14,239)
Asia reported 594K new cases (up from 529K) and 5,660 more deaths (down from 6,010)
North America reported 491K new cases (down from 550K) and 14,933 more deaths (down from 18,502)
Africa reported 72.3K new cases (up from 67.7K) and 2,029 more deaths (slightly down from 2,103)
Oceania reported 676 new cases and 6 deaths

Corners of the world


Brazil reported 496K new cases (up from 414K) and 12,328 more deaths (up from 9,960)
USA reported 400K new cases (down from 457K) and 9,981 more deaths (down from 12,481)
India reported 142K new cases (up from 113K) and 790 deaths (723 last week)
Iran reported 58.1K new cases (slightly down from 58.3K) and 557 deaths (613 last week)
Canada reported 24.8K new cases (up from 16.9K) and 253 deaths (236 last week)
South Africa reported 7,894 new cases (down from 8,201) and 613 deaths (782 last week)
Japan reported 7,561 new cases (slightly up from 7,256) and 332 deaths (397 last week)
South Korea reported 3,048 new cases (up from 2,732) and 35 deaths (42 last week)
Australia reported 81 new cases (63 last week) no deaths

Europe in detail

Italy is somehow on top again. The rest is either stagnating or increasing.

Deaths are still declining at least. It's a race between vaccines and new variants popping up in this huge Petri dish of over 20 million active cases. Israel resumed its downward trend, the vaccines are working.

Things are getting spicy. Does Germany still have millions of unused AZ vaccines?