haxxiy on 03 March 2021
To show how hard it is to escape the discerning gaze of cellular immunity, these are the results for T-Cell response to all VoCs out there. The two numbers represent respectively number and magnitude of preserved epitopes vs. the basal virus:
CD4+ T-Cell
84.4% - 89.6% B.1.1.7 (UK)
88.1% - 90% B.1.351 (SA)
95.7% - 94.3% P.1 (Brazil)
97.8% - 97.1% CAL20C (US)
CD8+ T-Cell
100% - 98.3% B.1.1.7 (UK)
97.3% - 98.4% B.1.351 (SA)
97.3% - 97.9% P.1 (Brazil)
97.9% - 97.8% CAL20C (US)
https://www.biorxiv.org/content/10.1101/2021.02.27.433180v1
