Uncharted: Golden Abyss last boss fight on hardest difficulty. It's not just annoying as hell, the controls also don't work like 50 % of the time. Screw dat.
edit: whoops, I just read last gen, sorry. But still, it sucked very hard! =P
Official member of VGC's Nintendo family, approved by the one and only RolStoppable. I feel honored.