Ninja Gaiden 1
The Adventures of Bayou Billy
All on the NES. I'm sure there are others, but that;s what comes to mind.
Oh yeah. Bayou Billy. I got that came because it tried to do so much. It had crazy variety but damn, it was hard. Especially the driving parts. Would break my thumbs! I did beat it, though. Probably the time in my life. Once, without the whip. That game. You die once and lose your powerups (whip, bullet proof vest, meat) and you're screwed. It was either never die or die and start over.