I would barricade the shit out of my doors/windows on the bottom floor. Then I'd go out onto the 2nd floor roof (its easy to get to) and take out as many as I can! I'm a gun owner so I'd snipe as many as I can. I have an SKS and about 1,600 rounds of ammunition right now so I'd be good for a while.
If I had time to prepare I would just get extra supplies (wood beams, locks, etc) for barricading my windows/doors and buy a good supply of bottled water, canned food, and other foods. And of course a good supply of coffee.
In the near future I plan on buying a shotgun and at some point an AR-15. So hopefully the zombies don't come till I have these!