Nothing correctly guessed so far, so let's add hints:
#50: Descent as guessed by Machina.
6 Degrees of Freedom.
Destroy the rebelling robots.
#49: Doom 64 as guessed by S.Peelman.
Not a port, but actually it's own title.
If that number in the title is a version number, than this series would've a *lot* of games.
#48:
Slice with your sharp dice the enemies.
RPG in which you advance the dice of the character classes.
#47: Crusader Kings III as guessed by Machina.
You could describe the game as monarchy simulator.
Third game in this series.
#46:
Other guests at Spiffo's restaurant may actually crave *you* more than a burger.
These are the End-Times.
#45: Ys VIII: Lacrimosa of Dana as guessed by Veknoid_Outcast.
Fill your improvised settlement with other survivors of the shipwreck.
You can always count on your friend that was with you in other games in the series as well to keep the settlement save and working.
