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There is a study, that apparently people with serious infection can develop antibodies against ACE2, so your own body. This doesn't sound great.
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0257016 Also, because of non-pharmaceutical interventions against COVID, we had a far slower flu season.

That may be a problem coming up, as it affects development of each years flu vaccines:

https://www.youtube.com/watch?v=S7XQ5ZNKDJo&ab_channel=SciShow



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