Madden. Because I hate sports games.
Gran Turismo and Forza, because I hate realistic/semi-realistic racing games.
Sonic has done a little bit better with Unleashed, and needlemouse seems good, so I'll spare Sonic.
Wii Music series (it will never get a sequel it needs to die before it's even turned into a series)
Imagine series. Party Babys... WHAT?!
Command and Conquer. Tiberian Sun was the last great C&C. RA2 did not have the epic feel of the first RA, and then after the takeover, EA tried to emulate what made the first games good in C&C3, but it's just not the same. C&C needs to rest in peace, or the IP needs to be sold to Petroglyph (old westwood).
Paper Mario. I Want Super Mario RPG2 :(
Call of Duty. Because Battlefield and MAG style FPS are so much more fun than CoD style FPS.