Antagonists other than Ganondorf/Ganon exist in the Zelda universe. Would you be disappointed if Ganondorf/Ganon is not the primary antagonist of Zelda Wii 2?
I think it would be a change of pace for a large console Zelda game to have multiple major antagonists. Maybe have mulitple villains working together like in Four Swords Adventure with Ganondorf and Vaati. What do other Zelda fans think?