Most of the main cast of Star Ocean 4, but Sarah in particular. Her voice made what was already an annoying character infuriatingly grating. Several characters in Xenoblade Chronicles, like Reyn, Juju, and Riki. While playing the game, it felt like there was a 50-50 chance that any new character introduced would end up just annoying me most of the time. It got better as the game progressed, but early on there were several characters I found myself hoping would not play a significant role in the story.

Wario and Waluigi. Just complete crap.

Wario is great but Waluigi is complete bullshit. Wario was in a real game and has real games. It was clever. M upside down is W. The fuck is a Waluigi? That's not clever. The fuck is an upside down L? He was made to be in shitty party games. Abomination of a creation for not real games. Trash like Mario Party.

This asshole from Last Window:

And of course the fucking Flower:

Saint's Row Relatable Zoomer Cast.

Nazeem the first boss in Skyrim.

This Bird from Spyro 2 that commits war crimes.

A main character integral to the plot of the Blood & Wine expansion for The Witcher 3, I won't spoil since it's tied to a sort of twist. People should know who I'm talking about.

Ha, great shout. Can't stand this guy.

I always hated Alfred in RE CV. My lord, did that laugh start to grate.