3 and for very diferent reasons:

1: Star Fox: At last the series is back and im a big fan. I even liked Dinosaur Planet.
2: Fatal Frame V: Fatal Frame is the only videogame series that has made me feel like a baby because of the fear.
3: Yoshi Wooly World to play it with my girlfriend and have an amazing time.

Honorable Mention: Xenoblade. But it´s not in my top 3 because its still a loing way before it releases.

XCX. No contest.
But second is tight right now. Star Fox got that nostalgia, but FAST Racing Neo scratches that F-Zero itch, and Yoshi looks quite good. Also have an eye on Fatal Frame and Genei Ibunroku #FE despite them not being my usual thing.

Zelda - as I'm a Zelda fan of course

XCX for me. i thought it would have an august or even a july release date then it was a december release. :(
i can wait, i'm currently playing Xenoblade so i can wait for XCX.

Zelda without hesitation.

It might be a bit far out, but LoZ has consistently been my favorite gaming series ever since I was a kid. Every new game release is like a personal holiday xD

X... Just X. Like, X man.

XCX

Yeah after watching the Treehouse gameplay I had a feeling certain polygons and physics would raise your interest. ;)

Zelda is easily head-and-shoulders above the rest for me but I am still very interested in Super Mario Maker; not just in getting my hands on it but in seeing how Nintendo markets it.

I see this mistake too many times. It's Tensei NOT Tensai.

But Shin Megami Tensei X Fire Emblem has been and will always be my most anticipated.