I loved the hell out of HR, played it on PC (launch game and some DLC, no director's cut version). I remember it running and looking great on both a Radeon 6950 2GB and a 670FTW (later SLI'd before replacing with 970s). Played smoothly at 1920x1200 with everything near-max on the 6950, and totally maxed on the 670. I need to load it up on the 970s and give it a replay.
So always happy for more Deus Ex if it's like any of the previous great games. I liked almost all of the previous ones. I know some fans are very pro/con here and there, but as different as they are I've still had a lot of fun, and the sci-fi presentation is better than almost anything else out there imho. It helps that I'm a big Blade Runner fan, so the dystopian world of technology, corruption, evil politicians and corporate leaders rings true even with what we know today, to say nothing of what will come with more and more high-tech centralized power.