U guys are taking what he said way out of context, I suggest reading the full answer before jumping the gun.
The original question was how can they expect to return to Nintendo like profits with their current businesses since 3DS has started to decline and Wii U costs alot to produce.
Iwata is in no way saying that they are banking on a single piece of software to fix their problems, he is just using Pokemon as an example that u can't count out a platform until all is said and done.
Basically he's saying with new software there is no reason that 3DS can't stop the decline or that Wii U can't continue to see inprovement.
Nintendo clearly isn't banking on a single piece of software to revitalize Wii U considering they have close to a dozen 1st/2nd party exclusives lined up for the year, games that belong to many different genres and aimed at different demographics. Things like Xenoblade and Zelda which are quite possibly Nintendo's biggest and most ambitious titles ever in terms of size, new ip like Splatoon and Devil's Third, the return of Star Fox after a decade, a new take on their most popular franchise ever in Mario Maker, and new quirky installments of Kirby, Yoshi, Mario Party while also trying to push Amiibo in new ways.
As for 3DS, they have a new revision that improves in almost every way, the long awaited remake of Majora's Mask, Monster Hunter 4, a new ip in Codename STEAM, a crossover of one of Japan's most popular mobile games, a port of Xenoblade which will help give franchise more exposure and help future installments, a new Fire Emblem which will hopefully help continue to grow the franchise, the localization of Youkai Watch which has gone on to be one of the most successful titles in Japan, alongside other unannounced things.
So just because Iwata says that a single game can change a platforms fate doesn't mean that's what they are banking on.