I don't like them both but I have to go with...............Japanese I guess. I would definitely go with Japanese if they would stop grunting a lot:P

off topic, love your sig, dunno why but there's something about the Infamous dude getting smacked by the train that makes me want the game more.

On topic, Japanese: hands down. sure Americans make some great ones but Japan edges it because you can get som truely "out there" stories.

Japan all the way...

@Ajescent

Thanks (even though I didn't make it)

I'm already hyped for the game, looking at the gif makes me want it more:P

The definition for anime is 'Japanese Animation' so a better term for this would be American and Japanese Animation.
Anime is my pick, I'm a big fan of animu :D Though I have to admit, american animation has come a long way... but it is still..... american :p

really it would be american cartoons... but you can't compare them. I love me some Spongebob, but anime is just tons tons deeper, and there are many different anime for a wide variety of ages, where american animation is really set for a younger audience, with the acception of a few shows, but they're all comedies (though I love comedy.)

Pokemon wins.
Beyblade came close.

EDIT: I just realised... i posted 2 Japanese cartoons my bad.

Samurai Jack came close!

Forgive my extreme ignorance of all things anime, but...what's American anime? Boondocks?

For some of you, this is what I mean by American anime

Dragonball Z, Pokemon and several others made my childhood sweet.

Shaman King, Cowboy Bebop, and several others made my adolscence sweet.

I'll go with Japanese.