Secret of Evermore (SNES) One of the best games ever created, but got shot down because it wasn't Secret of Mana 2.
WipeOut 64 (N64) Best WipeOut ever created, but somehow many people think it sucked (probably because it wasn't on a PlayStation console).
International Superstar Soccer 2000 (N64) Up until Fifa 08 (for me) the best footie ever created.
Zack & Wiki (Wii) Selling pretty well now, but still a great game that should have been so much more popular.
Boom Blox (Wii) let's hope it has legs, as of now, it's selling pretty bad.