NES, most. But second place, can't believe I am saying this, is the Switch. I mean the sales are crazy. It clearly demonstrates convenience over high-end graphics. The S2 is off to a great start. MS is working with Rog for a xbox handheld. Rumor has it Sony is going hybrid at some point as well. Feels like the Switch has forever changed the market. I still think NES is first, but the Switch would be second on my list.

Virtual Boy.

NES and it's not even close really. The entire modern game market basically traces back to there.

PS1 is overrated, it just took the 3rd party support that Nintendo already had for 10 years ... where do you think Final Fantasy and Metal Gear and Dragon Quest and Castlevania got popular? Capcom was already one of the most famous devs because of the NES and SNES, it's not like they just popped out of the ground with Resident Evil. Sega was already marketing towards older audiences/teenagers too, so the whole "Sony started marketing at non-kids!" thing is bunk too, Sega was doing that a generation prior already. 

Sony just got fortunate that Nintendo made an extremely stupid decision to use cartridges and the double whammy of Sega basically killing itself, leaving the PS1 with a wide open path. If the N64 used CD-ROM, I doubt the Playstation wins that generation at all, they'd have been no.2 and a distant no.2 at that. Even the PS1 OG controller design is basically a rip off of the Super NES controller and then they had to see Nintendo use analog + rumble on the N64 to copy that as well. They just copied a lot of the Super NES and added in more Sega style marketing (right down to their Sonic knock off of Crash Bandicoot). 

PS1

Me thinks NES era gaming was still seen as mostly toys for kids spend time. If things were kept as they were during NES era I don't think gaming would be as big as it is now

Simply put, newly games based on NES design are "retro" i.e. trying to capture older audiences with nostalgia

Games based on PS1 philosophy in other hand still push gaming forward, trying to capture new audiences

Conversely, 2D games trying to capture new audiences/pushing gaming forwards seems to be mostly based on old PC games, not NES games. They are generally simulators, CRPGs, 4x Strategy, RTS, Immersion Sims, and even Roguelikes

I honestly think NES is an object from the past, but this is me lol

I'm gonna throw in the OG Xbox as far as setting the template for basically every modern console now; standardized parts with PC-like architecture, (as opposed to the more bespoke custom stuff in say PS2) with a built-in storage drive.

In my opinion, the Atari 2600.

Even if there was the first gen before it, to me the 2600 was the true start of gaming.