Next batch of clues:

23. Git gud the first.

22. One of its main characters was voiced by an actor who just passed away yesterday (December 8)

21. You meet the love of your life only to find out you have to murder her and her entire family to save yourself..

23 is Demon's Souls probably. Maybe Dark Souls.

21: Definitely Link’s Awakening.

Nice thinking. And correct. I figured I would give the actors as second hint. But it never came to that.

As the other two have already guesses I go with #22: Fallout New Vegas

Second round of hints for the unguessed games.

#24 Guessed by The_Liquid_Laser: Return to Zork

#23 Guessed by The_Liquid_Laser: Fire Emblem Radiant Dawn

a) The only Wii entry (well, besides Virtual console releases) in this classic series featuring magic, shapeshifters and kingdoms.

b) Silver-haired maiden.

#22

a) This is the first entry in a series, where you command a group of units through various missions.

b) Steal… *ahem* research the technology from defeated enemies.

#21 Guessed by Darashiva: Deus Ex: Human Revolution

#20 (kinda) Guessed by The_Liquid_Laser: Fire Emblem Awakening

a) Prior to the release of the newest entry a few months ago, this game was the best-selling entry in an old series.

b) Three characters in Super Smash Bros Ultimate.

#24

Okami (PlayStation 2/4)

Change From Last Year: +10

I replayed Okami for the first time in over a decade earlier this year, and you might notice it has made a pretty notable jump up in my top 50 as a result of this. It was even better than I remembered, with so many wonderful small details I had completely forgotten in the years since my first playthrough bringing me so much joy as a I discovered all those things all over again. The visuals are still absolutely gorgeous, the music is stellar, the story is a wonderful take on a number of different Japanese legends and folk stories, and the characters are both charming and memorable in the best possible way.

The HD rerelease of the game was just the excuse I needed to play Okami again, and I'm glad I did. I consider this a must-play game to everyone, especially if you're a fan of Zelda style games.

23.  Fire Emblem Radiant Dawn?

20.  Fire Emblem Fates?

More clues:

19.  a)  In spite of this game being called a black sheep today, this game sold amazingly well.  It was almost impossible to find a copy of this game in North American stores even several months after its release.
b)  I don't think I've ever encountered someone who has said this is the greatest game of all time.  However the series this game is from has more than one game which is commonly called the greatest game of all time.

17.  A very popular strategy series, known for being on the PC, has this streamlined version of the game on PS3 and several other platforms.

16.  This arcade series popularized 4 player co-op.  This is the second entry.

Radiant Dawn is correct. Fate isn't, but I guess it has also three characters in Smash. Also I took the sales from VGC, but that stopped tracking some time ago. Looking at the shipped data accumulated, Fate actually is in front. So I guess my hint was misleading. I meant Awakening and I probably give it to you as you were close and my hint based on old data.