Yuffie and Aerith from Final Fantasy VII/Crisis Core.

They're both soooo annoying. Yuffie in the original FF VII is just a trash character. In Crisis Core, Aerith adds nothing to the game, and the two chapters focused on her are easily the low points from the game. Come on... You have to chase a child for twenty minutes.

Tingle from any/all the Zelda games he's in.

I really wished for Rico from Killzone 2 to be killed off. It's like your mother warning you when growing up, "be careful what you wish for, you might just get it."

The disappointment which was KZ:SF was as a result of my wishing for Rico to die. GG literally killed off everyone. They killed the characters, the story, the level design and content.

Kratos, Hope, and that autotune guy from Saints Row. Can't remember his name because it's 1 AM, and too lazy to google search it.

Rosalina in every game except galaxy games and maybe smash 4. She just seems so...out of place.

Ice Climbers in Brawl

Yeah autotune guy can't be wished away or defeated. You must go back in time and destroy the killer of hip hop, rap, RnB as well as human voice singing known as Will.I.Am to stand a chance. 

(there is a street fighter reference in there somewhere) 

I think it's time for the Halo franchise to move on from Cortana. Halo 4 should have been her grand finale.

Usually any over-sexulized character or any character that serve a little to no purpose. That would be like 75% of Jrpgs characters... quantity over quality.
Thankfully, the jrpgs scene looks promising nowadays with a diffrent take on characters and their bonds.

MasterChief in Halo 1, 2, 3, 4, and 5.

Aerith because #TeamTifa