What are some popular games that you've never played. It can be a gaming series,are whatever. I've never played any final fantasy games at all. I've never even played a demo of them are anything. I've only played a handful of rpg's in my life,so I guess that's why i've never even bothered with them. 

I've never played so many popular games that I don't know where to start. Slender I guess, lol.

Way too many to even count really.
Mass effect trilogy
Bioshock's sans Infinite
GTA Vice City
Red Dead Redemption
Any Call of Duty that was not set during WW2 except for Ghosts when MP went free this weekend on the PS4, won't play any unless they get back to the WW2 setting.
Half Life 2
Any Finał Fantasies sans FF12 for a few hours, nor any other JRPGs except for Pokemon.
Any 360 exclusives
Any Nintendo games since GBC
And so on and so on.

*gulp* Metal Gear Solid 3

TLoZ: Skyward Sword
Resident Evil 4
Mario Galaxy 2
The Last of Us (will play this on PS4)

Pokemon Red/Blue, Metal Gear Solid (Series), God of War (Series), Gears Of War (Series) are probably the biggest examples.

All Final Fantasy
All Mass Effect
All Elder Scrolls
The Gears of War (played the first one and it was shit)
Almost everything on PS3 (Don't have a PS3 :( )

The only popular game series that springs to mind that I’ve never played is bioshock. I played most of the PS3( which was the only console I didn’t own last gen) first party titles round a friends and have played most of the big Nintendo and Microsoft 1st,2nd and 3rd party games.

Pokemon after Gen 1

God of War series, Dead space series, Mass Effect series, Half-Life series, and I'm sure there are many, many more. These are just the first that come to mind.

Any of the Banjo Kazooie games
Goldeneye 007
Any Mario game post Sunshine
The Last of Us