All gameplay related:
"+ Environments are bigger than Uncharted's (3-4x the size, multiple paths in many areas), exploration is encouraged (for loot mainly, though you may find a key that'll be used for a safe somewhere around the map for example).
+ You can stealthily take out enemies or go all guns, but you'll be punished for the latter (low ammo). Sometimes you can just sneak by. "Choice-based" combat is the term I've heard used for it, and is fitting. Stealth works better than in Uncharted, and you don't get multiple hordes of enemies like you sometimes do in Uncharted.
+ Survival/rpg elements like looting and crafting are well done and paired well with the bigger environments
+ Enemies are smart. They'll flank you, they know when you're using guns or not and act accordingly, that kind of stuff. Maybe not as smart as initially thought, but still better than most games."