College assigned email address. I decided it was time to outgrow my old username usually handle, Dr Obvious. The name makes total sense so it's what I generally use, but whenever I tell anybody it, they always think it's twestern. Every time I have to actually tell someone my email address, they just assume I'm wrong and just assume I mean twestern and I always have to correct people.
I would change again but it's a massive hassle to change email address and remember different usernames for different places.