As a PC gamer I have never cared much about resolution. If I like the art style, I will play games at tiny resolutions. Just recently I played Spider Man 2 on the PS2 and loved it, but I had to switch to the Dolphin emulator because quick saves, the game technically looked a hundred times better yes, but I would have no problem going back.
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Deus Ex (2000) - a game that pushes the boundaries of what the video game medium is capable of to a degree unmatched to this very day.