Domestically it's still the #3 highest-grossing R-rated movie, though it's right on the verge of passing American Sniper. It still has about $21 million to go before it passes The Passion. Adjusted for inflation, though, Deadpool is down at #19 domestically for R-rated movies, and The Exorcist is #1 at $898M in 2016 dollars.
Still, kudos to Deadpool. It was a great movie and it deserved its massive success. $745M global and $350M domestic is still a remarkable achievement for an R-rated movie.