I get the feeling they aren't in any sort of rush to release a new handheld anytime soon but if they did I do think it could have success pending what they focused on and set for goals.
First, Nintendo has demonstrated over and over again that it's possible to rake in cash on smaller (relative) user bases so I think it'd be a good idea to work on a new platform that was cheap and fast to develop for with titles appealing to "on the go" gamers.
Secondly the ideal timing for such a device would get it all the attention it deserves with it possibly even riding on the success of ps4 if it came out somewhere around 6-7 years into the ps4 life cycle since the first major hardware accessory, Morpheus is coming out in the first 2-3 years.
To complete this overall strategy for success in the handheld sector, there needs to be a really really cool feature between the ps4 and psp3. Like holy shit I'm addicted to all this monster taming cool. Or like amiibo cool. Some sort of idea that I haven't thought of yet whilst laying here naked, sprawled out on my bed playing backseat CEO to a multinational multi billion dollar company.
I'm sorry, I forgot the question