Wii: Wii Fit. It's already sold 6 million for 2009. Also because it IS a game.
PS3: GT5
360: Modern Warfare 2

Well, seeing as how Halo Wars tanked in sales compared to Halo 3, I'm not expecting ODST to do much better. It may crack 5 million, but I don't know how much further. MW sold almost 7 1/2 million to this date, and the sequel should do better. I don't know. It seems like people would be burned out on Halo by now, but people are still playing Halo 3 online in thousands, and as one user mentioned, there will be a $30 price tag, and it doesn't require Halo 3 to play. The end of this year will be interesting in sales. I'll probably buy both.

I don't think Uncharted 2 will out sell MW2 on PS3

Xbox 360: Halo 3 ODST

PS3:MW2

Wii: No idea...

Uncharted 2 wont touch MW2.

Im pretty sure CGI was talking about exclusives only though :0

PS3 - Final Fantasy XIII, if it comes out around the holiday season. Maybe GT5 if it comes out.

360 - Halo: ODST

Wii - Well, let's just say it will have "Wii" in the title!

you split MW 2 sales by its platforms. so no on the 360 it should not out sell ODST unless ODST sucks and has major coverage of sucking 

RTS does not equal a shooter in terms of sales, and for one i wish they had put that game on PC as much as they push RTS on consoles it never feels right or controls right or is as epic.... halo wars was nice but still full of fail... 

I also expect MW 2  sales to be fairly spread out and for it too come out latter in the year the ODST, expect ODST to hold for they year 09 after that  I could see MW 2 out stripping ODST 

360 - halo:odst
ps3 - uncharted 2:among thieves
wii - wiifit+
ds - dragon quest 9
psp - not sure yet
pc - sims 3

X360: MW2
PS3: MW2
Wii: Wii Fit
DS: Pokemon Platinum
PSP: Monster Hunter 2G(Freedom Unite)

You expect Uncharted 2 to do what Uncharted has done lifetime, in a matter of weeks? yeah right ....