Well my collection is pretty limited at the moment but so far is:

1. Metroid Prime Pinball
2. Mario Kart DS (played friends copy)
3. Final Fantasy III
4. Super Mario 64
5. Brain Age

I'll let yu guys knoe hou Hoshigami works out, and Wall*E + Brain Age when I get more time with them.

1. Legend of Zelda Phantom Hourglass
2. Animal Crossing Wild World
3. Mario Kart DS
4. Advance Wars Dual Strike
5. Big Brain Academy

5.Super Mario 64 DS
4.Animal Crossing Wild World
3.Pokemon Diamond
2.New Super Mario Bros.
1.Professor Layton & the Curious Village

Mario Kart DS, New Super Mario Bros., Meteos, Zelda PH, Star Fox Command

1.) Elite Beat Agents & Ouendan & Ouendan 2
2.) Phoenix Wright 1, 2, 3 & Apollo Justice (Though I'm still on PW1, just yet)
3.) N+ (I know it's not out yet, but seriously, there's no doubt this will be right here once it does come out)
4.) Professor Layton
5.) Metroid Prime Hunters [Pending] (Barely played it at all, so this may change)
There are a lot of good games but there's usually some small thing that doesn't quite work, like the game is too short, or too easy, or too tedious, or the controls
just don't work well that make me not want to pick any of them for the Top 5 game list.
NSMB came across too short, Phantom Hourglass WAY too short.
I seriously hate the controls on Star Fox(would it have killed them to use the Dpad for Boost, Brake, Roll and Bomb? or at least give you the option for it?)
Mario 64 was great, but the controls were really rough(why couldn't they just keep the damn joystick touchscreen area still?)
Pokemon is okay, but seriously, it just feels like I'm playing Pokemon Blue, but with better graphics, more stuff tacked on, and different pokemon, and since I don't collect, that does nothing for me.
Front Mission is great, but frustrating and a little tedious, and it's just a port of the SNES version. though it is a fairly solid port.
Mario Kart is okay, but I really prefer a joystick, and I HATE the way teh item distribution works. Also the online was crap when I tried it last.

Trauma Center is okay, I'm still learning the system, I might like it, might not, we'll see how that goes.
I haven't played Hotel Dusk, Trace Memory, or Touch Detective at all, at least one of them might catch my interest.

1. Pokemon Diamond
2. Final Fantasy IV
3. New Super Mario Bros.
4. Mario Kart DS
5. Yoshi's Island DS

1. New Super Mario Bros.
2. Mario Kart DS
3. Tetris DS
4. Wario Ware Touched
5. Legend of Zelda: Phantom Hourglass