RE4 is an absolutely fantastic horror shooter.
Okami, The art is beautiful and fantastic, but honestly I was disapointed with the actual gameplay. I never finished it. But it is beautiful. And really, you probably will love it. I seem to be a minority.
I have not finished Okami either. I only played a couple of hours actually... And RE4 seems sorta dull. I'm really in the minority there as well, I guess.
@OP, I really hope you'll enjoy them, even though I didn't, and wish you many hours of happy gaming.. ;)