There is no radical religion or a religion that clashes with a culture. There are only radical people who use religion as an excuse to justify their radical ways by twisting things to suit them and their agenda.
However, you get radical people on all sides, those who stand for their radical interpretations of a particular faith and those who radically oppose a religion or culture by empowering extremists and their radical interpretations of any religion / culture / ideology. Both tend to be dead set in their belief that the most extreme, oppressive, violent etc version is the true version. They refuse to see it any other way, they refuse to reason and they are adamant to get rid.
Human history is full of examples and so humans we never seem to learn. Even within our own culture, our own communities and families it is in our nature to divide ourselves and fight.