I think you're underestimating how big ND has become post The Last of US.
TLOU remastered and Halo: MCC weren't that far apart in terms of opening numbers despite Halo: MCC being hyped up way more and releasing in the best month to launch games in.

I think Uncharted 4 will EASILY beat Halo 5 in worldwide numbers, though will likely lose in US. Halo games get like 80% of their sales in US while Uncharted popularity is more evenly distributed around the world. But seeing how XB1 is all but dead outside US Halo 5 will likely have to rely on US for up to 90% of it's total sales.

First of all it be handy if this site didn't massive under track the Uncharted series, with the popularity of Naughty Dog significantly increased since the release of the last of us, I wouldn't be surprised to see Uncharted out sell Halo.

Bold prediction : Uncharted in the Us > Halo in the Us.

There is a differens between bold and crazy...

Eh, even if the chance is lower than 10%, it's still here : D

I like the crazy user!!! :D

Added. :3

Likely Halo. Halo is the game that defines the Xbox. Uncharted I heard despite being loved by most Sony fans, doesn't have the biggest amounts of sales. Besides, it seems like not one game defines Sony, but a group of games do.

Halo 5

Uncharted will do 2 millions max week one and i don't see Halo 5 below 2 millions

I would say Halo 5 US>U4 Global, but not by that much

judging by the difference of install base and the fact that Uncharted will not have any internal competion...i would say uncharted have really good chance

MS will put all their card to fight against each other + multiplat,uncharted have only multplats to care about.Plus ND's image is "godlike" while 343i.....welp....