pipemania 3d?.... or every metroid ever? :D

Would it be Pikmin, by any chance?

Right?! It's not perfect by any means, but it's so fun at times! And to date it's still one of my favorite looking games, the fur always stuck out to me, too. That, and I just think the world itself looked incredibly vibrant. 

Nope.. tanooki 

hehe nail on the head, I loved the booklet with the lil pikmin crawling over the gamecube controllers so you got an idea of the scale of them compared to real life items, what is going on in shigzys head :) wonderful stuff.

also think ROBOTTECHHEAVEN has jumped the gun a wee bit on his list :D

My 44th is Spirit Tracks. While it is not the best handheld zelda, it is the 2nd best. When I bought the game at launch back in 2009 and started playing it, I had a lot of fun. I also liked that Nintendo let you controll Zelda (in a way).
Since 2009 I have finished the game twice and 100% once.

What a game.  This + EX2 were seriously under-rated, in my opinion.  Loads of fun.  And Doctrine Dark is an awesome character :D

#44 - Super Mario Galaxy 2 (Wii)

As correctly guessed by Miz, my number 44 is SMG2.  While there were things about this sequel which I considered a step back over the original, it was still an absolute juggernaut of a game that I thoroughly enjoyed all the way through.  The beautiful artstyle, colourful worlds, inventive platforming and awesome replayability just came together in one fantastic package.

Clue for my #43 - A game where if you were weak, you could call cousin vinnie for a bit of extra help.  Strange obsession with broccoli, too.

Thanks to college I missed a lot so

49. Disgaea 3
48. Pokemon blue
47. Metal Gear Solid 2
46. Boomerman (GB)
45. Monster Hunter Freedom United
44. Ratchet and Clant

My next game borrowed a lot of elements form other games that it was so plainly obvious, but still became a awesome game. And the main characters voice will give you eargasim

My #44, as guessed by Scoobes, is Far Cry Instincts. A remake of the PC hit, Far Cry Instincts is less open-ended and more linear than the original Far Cry, but adds several innovations that distinguish it as a unique experience.