Although its hard, I will try to stick to one to two titles per console. There will be exceptions
NES: Super Mario 3, Final Fantasy, Fire Emblem
Master System: Phantasy Star
TG-16: Air Zonk, Cadash
Genesis: Phantasy Star 4, Shining Force 2
Sega CD: Lunar 2: Eternal Blue, Lunar: The Silver Star, Shining Force CD
SNES: Final Fantasy IV, Super Mario World, Chrono Trigger
32X: Knuckle Chaotix, Virtua Fighter, Virtua Racing
Saturn: Panzer Dragoon Saga, X-Men VS. Street Fighter, Guardian Heroes
Playstation: Metal Gear Solid, Final Fantasy Tactics, Final Fantasy IX
N64: Super Mario 64, Legend of Zelda: Ocarina of Time, Perfect Dark
Dreamcast: Soul Calibur, Shenmue II, Street Fighter 3 Third Strike, CvS2
PS2: Final Fantasy X, Suikoden V, Suikoden III
Gamecube: Resident Evil 4, Fire Emblem: Path of Radiance, Baten Kaitos Origins
X-box: Star Wars: Knights of the Old Republic, NFL2K5, Jade Empire
360: Street Fighter IV, Mass Effect, Lost Odyssey, Tales of Vesperia
PS3: Valkyria Chronicles, Disgaea 3, Street Fighter IV
Wii: No More Heroes, The Godfather: Blackhand Edition, House of the Dead: Overkill
Gameboy: Final Fantasy Legend III
Lynx: Blue Lightning
Game Gear: Shining Force II: Sword of Hajiya
GBA: Tactics Ogre: Knight of Lodis, Golden Sun, Lunar Legend
DS: New Super Mario Bros., Final Fantasy IV, Disgaea DS
PSP: Final Fantasy Tactic: War of the Lions
PC: Dragon Age: Origins, Everquest 2: The Shadow Odyssey, The Last Remnant