No, I wouldn't invest. It's a sinking ship imho. Wii U won't have the novelty which the wii had and will fail IMO. 3ds will do fantastically well though and will sell well over 100m units I think, but it won't be enough...
My prediction threads:
Wii U will sell under 40m units (made on 14th September 2012)
PS Vita will sell under 20m units (made on 30th September 2012)
Wii U will sell under 7m in 2013 - I was right