Resident Evil 4 or Zack and Wiki. I only have money for on right now, and I never picked up RE4 last gen so it's all new to me. Zack and Wiki also looks great so I am in a bind.  The price difference doesn't matter to me, any advice is appreciated.

You know,I´d say Mario Galaxy since it´s almost here...but since you only mention RE4 and Z&W,I´d go with Z&W...it´s a title that´s very rare to come by nowadays.

I would say get Resident Evil 4 since its a classic and even better with the wiimote.

Such a hard choice, it really depends on the type of games you like. For me, personally, I like Zack and Wiki better but that could be different for you.

Resident Evil 4, in my experience, is a game you can pick up and play easily. Zack & Wiki takes devoted play time.

Both are good.

Doesnt matter really. Buy one now and one later. Both are must haves.

tanks for the advice everyone.

RE4 is only $30, while Zack and Wiki is $40.  Save the $10 and wait for Z&W to drop in price.  Or you could save even more and go used...

 You know, I find the very opposite to be true.  Zack and Wiki can be played in small doses, a level at a time.  Something like RE4 requires you to sink in some time, especially if you play like me at turtle speed making sure there are no zombies around teh next corner.

While I love Zack and Wiki, I would have to go with RE4.  Something just tells me you are getting a little more for your money in RE4.  I whole-heartedly support Zack and Wiki, but that has a lot to do with the fact that I think we should support crazy games as much as possible. 

I say RE4 then Zack and Wiki but when you go and get SMG make sure to get it at toys' r us to get a 25$ gift card and ur almost there to get the Z and W game.