As much fun as it would be to watch this happen, as a non-PlayStation owner, I actually think it's pretty empty posturing from a company that isn't as powerful as it thinks it is.
First of all, their status as "largest third-party publisher" includes Blizzard. Without Blizzard and WoW, I think they are about as big as EA. And they are dependant on Guitar Hero and CoD/MW. DJ Hero is probably not a game that is going to provide another hit of that size, and Tony Hawk Ride certainly is not... And in the meantime, Guitar Hero is a franchise in decline. Even if there is a long term future for music games, GH is wearing out it's mindshare grace period over Rock Band, which has the original GH visionaries behind it.
And in the meantime, EA has hit bottom and is plotting it's return, and Ubisoft's underdog status hasn't changed, and both of those companies are taking Wii more seriously, looking for new growth opportunities, because they don't think they're sitting pretty.
Basically, I think Activision could yet have the troubles that EA, THQ and Take-2 are going through in store for them in the future. And this statement, more than anything it says about Sony, sort of shows that they are in the same place EA was during the later PS2-era, where they think they are the kings of the world, but don't have a long term plan, and don't even know it.
"[Our former customers] are unable to find software which they WANT to play."
"The way to solve this problem lies in how to communicate what kind of games [they CAN play]."
Satoru Iwata, Nintendo President. Only slightly paraphrased.