Valkyria Chronicles : your enemies are also living breathing humans and they're fighting for their homelands

Star Ocean 4 : in the future everyone looks like a teenager and with a voice that doesnt fit.

MGS4 : Snake is the Shit

Lost Odyssey : your daughter doesnt die when she fall off a 30 feet high cliff

Resident Evil : Steriod's make you look alot bigger than what you used to in PS1

Assasin's Creed : When you kill someone , hold your hand and pray... no seriously it fucking works!

Madworld

I Have no mouth, and I must Scream:

Assasin's Creed : When being chased by guards and your the only person wearing a white hoodie sit on a bench in broad daylight and no one will notice you.

Metal gear- When infiltrating kneel on the ground and yelling into your ear piece wont get you noticed or caught.

Bioshock- Despite you crash landed at a light house and could just wait or even call for rescue, instead would you kindly take the elevator downwards into a mutated hell.

Resident Evil 5- Despite all the members of a military group are heavily armed and have more armored vehicles...they'll die yet you'll survive with two not so armed people.

Street Fighter series- Apparently martial artists are more valuable than gold, oil and weapons to taking over the world instead.

Majora's Mask has made me think a lot about life, the game just goes so amazingly deep. That game is one of the most amazing things I've ever seen in this life.

 Well said!