That would be a great idea to include all 4 regions on the Wii, where you could get them all but they should make some of them hard to obtain. They should make sure the maps are totally different too and make it so you don't get all the pokemon in the same places as their other iterations. That way it would be a whole new RPG for the Wii rather than just playing all 4 stories you did on GB/A/DS. Yes apart from that i think they have flogged the series to death. I mean look at the legendary, arceus. He's a GOD pokemon. How could they possibly top that? I think they have taken it as far as it could go on DS. They can't possibly make any new pokemon, legendary or not, come across as any more"awesome." Any new pokemon will just become boring i think.
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In my opinion the N64 was not just the best console of the 5th gen but, to this day the best console ever created!