Depends if it's 3rd person. Females tend to block less of the screen in third person.

I always choose Male unless its like an MMO where the characters have different genders but the female has cooler moves than I choose the female.

Depends on the game. For MMOs, I almost always choose female because they tend to have much more options for character creation and outfits. For most single player games, I tend to pick male.

Whichever suits me. Often I feel the male characters look stupid or the female characters look more interesting.

Always play as male, unless there's a trophy I should get by playing as a female, like in Saints Row The Third and IV.

I always play male because i believe that makes me relate to the character i'm playing more.

If i chose female i probably wouldn't take the game very seriously. It's a bit like a troll.

Both

I pick Male most of the time but sometimes I choose female, it all depends the game.

Usually female, for several reasons.

1 - I tend to favor smaller, faster characters. Thieves, Rogues, Assassins, and so forth. Females often fit that better.

2 - I like to play a role that is a bit different from reality. Being a female character changes up the perspective somewhat.

3 - Honestly, many pre-made male characters are terrible. I'm tired of ex-soldiers. Female characters often have better back-stories.

4 - Related to #3 but I really dislike "super macho" types, be they male or female. Give me someone smart and tactical.

5 - I enjoy looking at females more than males and female characters tend to be designed to be more visually appealing. As I very much like different outfits and gear, I care about how my character looks.

Either. I have a male character in X, and a Squidgirl in Splatoon, for example.