Yes it's possible but Nintendo would have to make some major, major changes in how they view hardware and how they compete in the general marketplace.
If it's another "hey we're Nintendo, we're going to make a weird console" ... then no it won't get a lot of third party support unless it has a controller that sells to soccer moms/dogs/cats/some other audience that won't buy a console.
It must be a forward thinking platform of some kind too. Simply releasing a "Nintendo PS4" mid-cycle even if it is easy to develop for or whatever will not work either. It won't have the userbase the PS4/XB1 have so it can't be a priority for developers and it will be quickly outdated by the PS5/XB1 (same thing that happened to the Dreamcast, though the Dreamcast was actually far more powerful than the N64/PS1).
Nintendo needs to figure out an answer to the mid-cycle Dreamcast problem.












