I'm going to go with mario and sonic olympics on this one, we all had no doubt that this game would sell reasonable on brand name(s) alone, however i think this will be a multiple million seller.

Anyone else have some other leftfield predictions? 

I all platforms are counted, GTA4. If only a single platform. I say Halo3.

gta4 and halo3 are hardly leftfield predictions kwaad

and yes any system 

I think Wii Health will be the Surprise hit of the year.

Too Human

I also think the Wii Health Pack will be a smash hit. There is too much diet craze for it not too.

I'll take a longshot, Bob Ross: The Joy of Painting. Hardcore gamers will laugh at me, but something like this could become a pop hit.

That is what I am thinking. there will be many coach potatoes who will buy it like people bought Brain Age. fad or not it will sell andit will generate news stories about it hyping it even more.

 haha i remember when ign announced this ages upon ages ago.

 I'll second your motion on this being a hit as well

Its not exactly a "minor" title, but I sort of agree on this one. I think Treasure Island Z could be huge...