I have some that are keepers. I won't trade them in because I enjoy then so much (Oblivion, Tron Evolution, Arkham Asylum, both Endless Oceans, Dragon Age Ultimate Edition...). But, I have made some mistakes in the past, trading a few games that I should have kept (Enslaved and Alan Wake). But others, I have no problems selling while their value is still high enough (Dead Space 2, Blood Stone, Shattered Dimensions). I have no regrets for these.
And I have fun finding games for the PS2. With those, I take my time because I know they will be keepers. So far, I have Final Fantasy X & XII, Ico, Shadow of the Colossus, Silent Hill 3 and Beyond Good and Evil. They are all in near-mint condition and building this collection is really cool as I feel each game is worth it.