I hate it when the bosses are too easy, especially the last boss.

whenever games randomly crash like fallout does constantly

Intant death spikes!

The beginning in most games where you can't skip them when there really boring and take forever to finish. Twilight princess is notorious for this imo.

I get most irritated by bad game design and stories that I can't believe because of one thing or another.

As mentioned before I hate it when a game is difficult because of bad level design. I also hate a bad camera that makes a sore experience 

i also hate when you are supposed to be this super being yet you still die quickly like crysis and bioshock 2

annoying boss fights like the one in Metroid other M, i just hate those ***** bastards. they did not make the boss fun just annoying.

I hate that Zelda and Mario bosses are so easy too beat. at least make Zelda bosses as hard as those in Metroid Prime games

I hate long cut scenes as I want to play the game not watch a movie :P  

turn based games turn me off as do racing games except for burnout

Terrible design choices, like resistance, man that game is so terrible.