I keep my games, but yeah, some I won't ever touch again.

Uncharted 2 (single player) - Flipping amazing, but I won't play this again. Maybe in 20 years I might get the "remember that awesome game?" moment and want to play it then.

Darksiders - Awesome game, but it's pretty long and by the time I got towards the end I was started to get annoyed by the mini-games/puzzles.

FF13 - Good game, almost done with it and wont touch it again.

FF8 - Great game but I will probably never touch again.

lol I remember Adventures of Bayou Billy.

Anyways OT: Probably any Castlevania game, I hate it when they don't include the hardest mode from the beginning.

• Secreto of Mana: Its an excellent game but I cannot play it again. I don't know why
• Saga Frontier: you won't touch that disk after completing all stories
• Duke Nukem 3D : after completing it once (without cheats) I don't want a other complete playthrough
• Diablo I/II : areas are way too long and crowded. great for completion but after that... you start thinking it twice
• Baldur's Gate II: love that game but I won't play it again, is too long
• FFX : the first game I sold right after I completed it
• Gran Turismo in simulation mode : After getting all cups... I only play arcade

Dude, yes...I continue working my way towards beating the campaign on veteran, and although the game is sweet, and I loved (MW2 I'm talking about though) the campaign on the 2nd or 3rd difficulty (really don't remember which I did), I am getting raped on veteran, and as soon as I finish it, I will never ever go back to that crap again.

I play most of the games I buy only once in my life. If I'd ever cared for replay value of games which have a proper ending I wouldn't be the adventure game fan I am.

The only ones I play more often are the ones which are meant to be played forever anyway (e.g. Civilization I, II and IV, Anno 1701, Settlers II, SimCity 2000, Master of Magic, any Tetris, Clubhouse Games...).

There's one "forever" franchise though which I don't ever want to touch again: The Sims.

Back in 2000 I bought the first Sims game and played it for some weeks. I thought and still think it was another typical, simple-yet-brilliant Will Wright gameplay idea, but unlike SimCity playing The Sims wasn't fun, felt very strange and just isnt' for me.

For some weeks I searched for jobs on a virtual PC in a game on my actual PC, I told my avatar to got to the toilet and forgot to go there myself, I tried to built my virtual dream house but in real life the last thing I'd want to do is building a house, I tried to make as many virtual friends as possible but in real I'm glad that most of the people I ever met will never be my friends, I sent my avatar to the gym regularly but in real life I think gyms are one of the saddest inventions of modern society and I'd rather commit sepukku than visit one myself.

The strange Sims experience 10 years ago prepared me for a future gaming experience which I decided to avoid either when it became popular: Online gaming.

Probaly Monster Hunter TRi, since if I suddenly lost all my date I wouln't replay it

And professor Layton series, the best DS games but there's not much point to replay them

Red Dead Redemption, I got caught up in the hype and bought it. I regret buying it right away, I never beat it and I'm thinking about selling it, which is rare for me because I almost never sell my games. There is just nothing that makes me want to go back to it.

On the other hand, I love Valkyria Chronicles! Playing it my 2nd time now (started new game right after I beat it the first time) and it is so much fun! I will definitely be holding on to this gem.

Deathspank

Uncharted 2 - Got bored after finishing it 5 times in a row

Wipeout HD - 

After platinuming this game, you'd never play it. Ever. Its torture. Elite Campaign completion will get you gangraped by people with 15 inch cocks with the girth the size of a tennis ball. Getting to Zone 75 will cause you to become so damn frustrated. Hanging on at Zone 74 is like repeatedly stopping yourself from ejaculating. The beat Zico trophy is another utter bitch. 

After you finally platinum this game (and thereby become superior to every other racing gamer who ever lived), you'll not want to play it ever again. You'll shriek at hearing its very name.

As much as I LOVE Assassin's Creed II, I'd never play it over again.