Looking at historical software, and what has been released, I believe the following titles / genres constitute missed opportunities for third parties...

Wii:

Street Fighter (SFII had a 600k opening on SNES in Japan...6m ltd - worth a shot, no?)

Soul Calibur (1m on DC & GC...i mean come on)

Resident Evil 5 / new Resident Evil (previous new REs did 1m on N64 / GC, ports of RE4, others did well)

Puzzle games: Wetrix / Puyo Puyo / NES-N64 had tons / new stuff like them would probably do well with sequels

Turok (1m on N64

mainline Mortal Kombat (1m on various Nintendo systems)

Final Fantasy XII / Cell shaded Final Fantasy XIII (would have made Wii rpg system with PS2-like costs on dev side)

Some random stuff that may have done well pushing Wii hw in stylized, modern fashion: 2D Mega Man / 2D Sonic / Jet Set Radio / UFC / MMA /  2D Rygar / Shinobi / Panzer Dragoon / 2D Castlevania / 2D Final Fight / Powerstone / 2D Bionic Commando / 2D Double Dragon / Final Fantasy Tactics/ Devil May Cry

PS3 / X360

Jet Set Radio / Panzer Dragoon / Shinobi / Phantasy Star / Nights from Sega (these all seem like 500k hits)

Dragon Quest/ Final Fantasy Tactics (on Wii and portables)<

Onimishua / Powerstone / Dino Crisis  / Powerstone from Capcom (Dino Crisis strikes me as a huge HD hit...)

Streets of Rage / Final Fight / Double Dragon (update these in modern stylized 2D and they'd do well somewhere..)

Sim City (nostalgia alone).

What do you think? Am I missing anything obvious?

Gears of War, Metal Gear Solid 4, and to a lesser extent Mass Effect. I'm sure those would have been able to sell on other platforms (PC/360/PS3). Granted in the long-run what those developers did may have been the right thing to do.

With respect to the 360, if Gears and Mass Effect were released on the PS3, then IMO it would have been a significant blow to the platform's sales. Third party developers want a competitive market too, so in the long-run if their 'exclusive' support helped to establish a healthy market for their games to be released on then it's well worth it.

The same goes for the PS3 with Metal Gear Solid 4, I remember many proclaiming it to the reason to own a Playstation, one of the first must have titles. I'm not sure how much longer the next big exclusive PS3 was from release, but the sooner the better no doubt.

so everything on the wii = money? if not wii = lost money?

You forgot Chex Quest my good man. Easily over 1 million on all. :)

When it comes to HUGE names like Resident Evil and Street Fighter (also, names that have proved selling well on Nintendo platforms), yes. I'm not saying a GTA should head to the Wii but come on, the lack of a third person RE on the system is plain simple ridiculous.

scratches head.

Goes into another thread

Yeah I somewhat got this feeling too.

OT - Halo 3 on PC? More PS2 collections for the PS3? Kinect games on the Wii?

I will always commend TheSource when it comes to statistical data and whatnot (going to school for business administration with a huge marketing background aimed at the video game industry), so all of his info is well appreciated. However I do feel this thread goes into the realms of the diehard Wii loving aspect which bothers me. How about mentioning how the new Castlevania exclusive announced for XBL should also go to the PSN since SOTN was such a success on a previous Sony system? How about The Last Story or Xenoblade going to 360 and PS3 since both have proven to have a healthy RPG fanbase? Would also help to mention NMH on PS/360 would be a great idea since the stylized action genre sells well on those systems or at the very least traditionally have (DMC series on PS2), bayonetta, etc. Would be great to see it a little bit more spread out across the systems instead of seemingly blatant bias. Perhaps I have misinterpreted the information given and if I have, to TheSource, I apologize in advance.

I think Powerstone would work well on PSN and XBLA as well. I've actually been hoping for that one. Also I think the idea of a cell-shaded FF13 would have slowed the development time even more and may not have been as lucrative as you think.

You see as crazy as it may sound and in the Wii's defense an FFvs13 with a Xenoblade art style would work and would sell to another system that has a TRUE RPG fanbase just like the Playstation, as it was in Nintendo where Final Fantasy started along with other great rpg's. If it has a battle system remotely close to KH the motion controls CAN be properly applied as an option and could definitely work.